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Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 493-502 doi: 10.1007/s11684-022-0946-x

Abstract: In this work, we investigated whether the variant allele frequencies (VAFs) of ALK fusions can

Keywords： next-generation sequencing     fluorescence in situ hybridization     immunohistochemistry     variant allelefrequency     intratumoral heterogeneity     targeted therapy    

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Studies on Malate Dehydrogenase Ⅱ (MDH Ⅱ ) Isozymes in Different Races of Apis mellifera ligustica

Chen Shenglu,Bao Xiuliang,Su Songkun,Liu Yanhe

Strategic Study of CAE 2000, Volume 2, Issue 1,   Pages 57-61

Abstract: honey bee (Ee) and Australian Italian honey bee (Eo) have been used to study the genotype, genotype frequency, allele frequency, heterozygous and homzygous degrees of the malate dehydrogenase Ⅱ (MDH Ⅱ ) isozymesThe allele frequencies are a (0.184), b (0.091), c (0.726) in Ea; a (0.067), b (0.090), c (0.717) inresults of test-independence show that there are significant differences in the distributions of genotype frequency, gene frequency, heterozygous and homozygous degrees among five races of Apis mellifera.

Keywords： races of Apis mellifera malate dehydrogenase (MDH)     genotype     allele frequency     heterozygosity    

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BULKED SEGREGANT RNA SEQUENCING (BSR-SEQ) IDENTIFIES A NOVEL ALLELE ASSOCIATED WITH WEEPING TRAITS IN

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 2,

Abstract: The Pm024074(PmUGT72B3) allele, belonging to the UDP-glycosyltransferase superfamily

Keywords： BSR-seq / PmUGT72B3 / Prunus mume / UDP-glycosyltransferase / weeping shoots / WGCNA    

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BULKED SEGREGANT RNA SEQUENCING (BSR-SEQ) IDENTIFIES A NOVEL ALLELE ASSOCIATED WITH WEEPING TRAITS IN

Xiaokang ZHUO, Tangchun ZHENG, Zhiyong ZHANG, Suzhen LI, Yichi ZHANG, Lidan SUN, Weiru YANG, Jia WANG, Tangren CHENG, Qixiang ZHANG

Frontiers of Agricultural Science and Engineering   Pages 196-214 doi: 10.15302/J-FASE-2020379

Abstract: The ( ) allele, belonging to the UDP-glycosyltransferase superfamily containing the coniferyl-alcohol

Keywords： BSR-seq     PmUGT72B3     Prunus mume     UDP-glycosyltransferase     weeping shoots     WGCNA    

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A frequency error estimation for isogeometric analysis of Kirchhoff–Love cylindrical shells

Frontiers of Structural and Civil Engineering doi: 10.1007/s11709-023-0006-x

Abstract: A frequency error estimation is presented for the isogeometric free vibration analysis of Kirchhoff–LoveBy analyzing the discrete isogeometric equations with the aid of harmonic wave assumption, the frequencyIn particular, the governing relationship of the continuum frequency for Kirchhoff–Love cylindrical shellsis naturally embedded into the frequency error measures without the need of explicit frequency expressionsNumerical results not only thoroughly verify the theoretical convergence rates of frequency solutions

Keywords： isogeometric analysis     Kirchhoff–Love cylindrical shell     free vibration     frequency error     convergence    

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Calculation of collision frequency function for aerosol particles in free molecule regime in presence

Xiaowei LUO, Yannick BENICHOU, Suyuan YU

Frontiers in Energy 2013, Volume 7, Issue 4,   Pages 506-510 doi: 10.1007/s11708-013-0275-5

Abstract: The collision frequency function for aerosol particles has already been calculated for the free moleculeforce, electric force and molecular forces, created by particles themselves, recalculated the collision frequencyAttractive forces increase naturally the collision frequency, while repulsive forces decrease it.

Keywords： aerosol particles     collision frequency function     coagulation    

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Fuel variability effect on flickering frequency of diffusion flames

Jizhao LI, Yang ZHANG

Frontiers in Energy 2009, Volume 3, Issue 2,   Pages 134-140 doi: 10.1007/s11708-009-0034-9

Abstract: The intent of this study is to investigate the fuel variability on the flickering frequency of diffusionIt was found that the low frequency oscillation of flow and flame structures depended only weakly onWhen a mixture of methane/propane at a ratio of 1:1 was used the peak flickering frequency was aroundMechanisms thought to produce changes in the dynamic response and frequency harmonics were discussed.

Keywords： fuel variability     flickering frequency     diffusion flames     dynamics of combustion    

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Capacity limitation of nuclear units in grid based on analysis of frequency regulation

Yiping DAI, Pan JIANG, Lin GAO, Weimin KAN, Xiaoqing XIAO, Ge JIN

Frontiers in Energy 2012, Volume 6, Issue 2,   Pages 148-154 doi: 10.1007/s11708-012-0174-1

Abstract: Based on the analysis of frequency regulation, mathematic models for nuclear units in the grid are establishedThe relationship between different styles of frequency regulation and the allowable capacity of the nuclear

Keywords： nuclear units capacity     overspeed     primary frequency control (PFC)     second frequency control (SFC)    

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Oscillation frequency of simplified arterial tubes

Hui AN, Fan HE, Lingxia XING, Xiaoyang LI

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 3,   Pages 300-304 doi: 10.1007/s11465-009-0038-5

Abstract: To construct the spatial kinetic equation of an arterial tube and obtain its radial natural frequencyThe results show that the first-order frequency is 15.8 Hz and the obtained exact analytical solutions

Keywords： spatial kinematics     natural frequency     finite element method    

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Parameter identification of interconnected power system frequency after trip-out of high voltage transmission

Xuzhan ZHOU,Shanshan LIU,Mingkun WANG,Yiping DAI,Yaohua TANG

Frontiers in Energy 2014, Volume 8, Issue 3,   Pages 386-393 doi: 10.1007/s11708-014-0323-9

Abstract: Accurate modeling and parameters of high voltage (HV) grid are critical for stability research of system frequencyIn this paper, simulation modeling of the system frequency was conducted of an interconnected power system

Keywords： high voltage (HV) grid     frequency stability parameter identification     primary frequency regulation (PFR    

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Dependence of error sensitivity of frequency on bias voltage in force-balanced micro accelerometer

Lili CHEN, Wu ZHOU

Frontiers of Mechanical Engineering 2013, Volume 8, Issue 2,   Pages 146-149 doi: 10.1007/s11465-013-0260-z

Abstract:

To predict more precisely the frequency of force-balanced micro accelerometer with different biasvoltages, the effects of bias voltages on error sensitivity of frequency is studied.The resonance frequency of accelerometer under closed loop control is derived according to its operationsensitivity with designed parameters of structure, circuit and process error can be used to predict the frequency

Keywords： Micro-Electro-Mechanical Systems (MEMS)     micro accelerometer     force-balanced micro accelerometer     frequency    

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Remote calibration system for frequency based on in-place benchmark

Xiaobin HONG, Guixiong LIU, Zhuokui WU, Xipeng DU,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3,   Pages 316-321 doi: 10.1007/s11465-010-0021-1

Abstract: calibration mode based on material object reference, a new model of a remote calibration system for frequencysome key problems for the remote calibration system is particularly discussed, including the time and frequencybenchmark receiving module based on global positioning system (GPS), frequency comparison based on aphase method, frequency division based on dual high-frequency phase locked loop (PLL), and remote calibration

Keywords： remote calibration     in-place benchmark     frequency comparison     global position system (GPS)    

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Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness

Wenjun Xia,Fei Liu,Duan Ma

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 137-142 doi: 10.1007/s11684-016-0449-8

Abstract: On the basis of the frequency of hearing loss, hereditary non-syndromic hearing loss can be divided intohigh-, mid-, low-, and total-frequency hearing loss.Up to now, merely 7 loci have been linked to mid-frequency hearing loss.Only four genetic mid-frequency deafness genes, namely, DFNA10 (EYA4), DFNA8/12 (TECTA)This review summarizes the research progress of the four genes to draw attention to mid-frequency deafness

Keywords： hereditary non-syndromic hearing loss     mid-frequency hearing loss     deafness genes    

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Time-domain and frequency-domain approaches to identification of bridge flutter derivatives

Zhengqing CHEN

Frontiers of Structural and Civil Engineering 2009, Volume 3, Issue 2,   Pages 173-179 doi: 10.1007/s11709-009-0034-1

Abstract: study was made to identify the flutter derivatives of each model by using a time-domain method and a frequency-domainIt was shown that all the flutter derivatives of the thin-plate model identified with the frequency-domainMore precisely, the frequency-domain method usually results in smooth curves of the flutter derivatives

Keywords： long-span bridges     wind-induced vibration     flutter derivatives     forced vibration test     time-domain method     frequency-domain    

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Analysis of frequency characteristics of compliant mechanisms

WANG Wenjing, YU Yueqing

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 3,   Pages 267-271 doi: 10.1007/s11465-007-0046-2

Abstract: differentials of a stiffness matrix to design parameters, a method for calculating the sensitivity of natural frequencyThe numerical simulation results indicate that the design parameters have an impact on the frequencycharacteristics of the compliant mechanisms and the proposed method is more accurate and convenient for analyzing frequency

Keywords： compliant mechanisms     convenient     sensitivity     work     analysis    

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Title Author Date Type Operation

Potential unreliability of ALK variant allele frequency in the efficacy prediction of targeted therapy

Journal Article

Studies on Malate Dehydrogenase Ⅱ (MDH Ⅱ ) Isozymes in Different Races of Apis mellifera ligustica

Chen Shenglu,Bao Xiuliang,Su Songkun,Liu Yanhe

Journal Article

BULKED SEGREGANT RNA SEQUENCING (BSR-SEQ) IDENTIFIES A NOVEL ALLELE ASSOCIATED WITH WEEPING TRAITS IN

Journal Article

BULKED SEGREGANT RNA SEQUENCING (BSR-SEQ) IDENTIFIES A NOVEL ALLELE ASSOCIATED WITH WEEPING TRAITS IN

Xiaokang ZHUO, Tangchun ZHENG, Zhiyong ZHANG, Suzhen LI, Yichi ZHANG, Lidan SUN, Weiru YANG, Jia WANG, Tangren CHENG, Qixiang ZHANG

Journal Article

A frequency error estimation for isogeometric analysis of Kirchhoff–Love cylindrical shells

Journal Article

Calculation of collision frequency function for aerosol particles in free molecule regime in presence

Xiaowei LUO, Yannick BENICHOU, Suyuan YU

Journal Article

Fuel variability effect on flickering frequency of diffusion flames

Jizhao LI, Yang ZHANG

Journal Article

Capacity limitation of nuclear units in grid based on analysis of frequency regulation

Yiping DAI, Pan JIANG, Lin GAO, Weimin KAN, Xiaoqing XIAO, Ge JIN

Journal Article

Oscillation frequency of simplified arterial tubes

Hui AN, Fan HE, Lingxia XING, Xiaoyang LI

Journal Article

Parameter identification of interconnected power system frequency after trip-out of high voltage transmission

Xuzhan ZHOU,Shanshan LIU,Mingkun WANG,Yiping DAI,Yaohua TANG

Journal Article

Dependence of error sensitivity of frequency on bias voltage in force-balanced micro accelerometer

Lili CHEN, Wu ZHOU

Journal Article

Remote calibration system for frequency based on in-place benchmark

Xiaobin HONG, Guixiong LIU, Zhuokui WU, Xipeng DU,

Journal Article

Research progress in pathogenic genes of hereditary non-syndromic mid-frequency deafness

Wenjun Xia,Fei Liu,Duan Ma

Journal Article

Time-domain and frequency-domain approaches to identification of bridge flutter derivatives

Zhengqing CHEN

Journal Article

Analysis of frequency characteristics of compliant mechanisms

WANG Wenjing, YU Yueqing

Journal Article